O'Donnell Lab Collaborators

Jeffrey Brodsky, PhD (University of Pittsburgh)

Position: Professor, Avinoff Chair of Biological Sciences

 

Area of Study: Protein quality control

 

Website: http://www.biology.pitt.edu/person/jeffrey-brodsky

 

Contact: jbrodsky@pitt.edu

 

Co-authored Papers:

Hager, N.A., Kraswoski, C.J., Mackie, T.D., Kolb, A.R., Needham, P.G., Augustine, A.A., Dempsey, A., Szent-Gyorgyi, C., Bruchez, M.P., Bain, D.J., Kwiatkowski, A.V., O'Donnell, A.F., Brodsky, J.L. Select a-arrestins control cell-surface abundance of the mammalian Kir2.1 potassium channel in a yeast model. The Journal of Biological Chemistry. 293 (28):11006-11021.

Mackie, T. D., Kim, B.Y., Subramanya A.R., Bain, D.J., O'Donnell A.F., Welling, P.A., Brodsky, J.L. The endosomal trafficking factors CORVET and ESCRT suppress plasma membrane residence of the renal outer medullary potassium channel (ROMK). The Journal of Biological Chemistry. 293(9):3201-3217

Prosser, D.C., A.E. Pannunzio, J.L. Brodsky, J. Thorner, B. Wendland, and A.F. O'Donnell. (2015) α-Arrestins participate in cargo selection for both clathrin-independent and clathrin-mediated endocytosis. The Journal of Cell Science 128 (22): 4220-4234.

 

C.G. Alvaro, A.F. O'Donnell*, D.C. Prosser, A.A. Augustine, A. Goldman, J. Brodsky, M.S. Cyert, B. Wendland, and J. Thorner. (2014) Specific α-arrestins negatively regulate Saccharomyces cerevisiae pheromone response by down-modulating the G-protein coupled recpetor Ste2. Molecular and Cellular Biology 34(14):2660-81.              

*Co-first author

 

Hecht, K.A., A.F. O'Donnell, and J. Brodsky. (2014) The proteolytic landscape of the yeast vacuole. Cellular Logistics 4(1): e28023.

Martin C. Schmidt, PhD (University of Pittsburgh)

Position: Associate Professor

 

Area of Study: Snf1 kinase of yeast

 

Website: http://www.mmg.pitt.edu/node/301

 

Contact: mcs2@pitt.edu

 

Co-authored Papers:

 

O'Donnell, A.F., R. R. McCartney, D. G. Chandrashekarappa, B. Zhang, J. Thorner, and M.C. Schmidt. (2014) 2-Deoxyglucose impairs yeast growth by stimulating Snf1-regulated and α-arrestin-mediated trafficking of hexose transporters 1 and 3 in Saccharomyces cerevisiae. Molecular and Cellular Biology, 35(6):939-55.

 

Nathan L. Clark, PhD (University of Pittsburgh)

Position: Assistant Professor

 

Area of Study: Molecular Evolution, Comparative Genomics

 

Website: https://www.csb.pitt.edu/faculty/clark/

 

Contact: nclark@pitt.edu

 

Michael Knop, PhD (University of Heidelberg)

Position: Professor

 

Area of Study: Regulation of cellular morphogenesis and cell signaling

 

Website: http://www.zmbh.uni-heidelberg.de/Knop/default.shtml

 

Contact: m.knop@zmbh.uni-heidelberg.de

 

Beverly Wendland, PhD (Johns Hopkins University)

Position: Professor, James B. Knapp Dean of the Krieger School of Arts & Sciences

 

Area of Study: Molecular mechanisms and regulation of endocytic vesicle formation

 

Website: http://bio.jhu.edu/directory/beverly-wendland/

 

Contact: bwendland@jhu.edu

 

Co-authored Papers:

 

Prosser, D.C., A.E. Pannunzio, J.L. Brodsky, J. Thorner, B. Wendland, and A.F. O'Donnell. (2015) α-Arrestins participate in cargo selection for both clathrin-independent and clathrin-mediated endocytosis. The Journal of Cell Science 128 (22): 4220-4234.

 

C.G. Alvaro, A.F. O'Donnell*, D.C. Prosser, A.A. Augustine, A. Goldman, J. Brodsky, M.S. Cyert, B. Wendland, and J. Thorner. (2014) Specific α-arrestins negatively regulate Saccharomyces cerevisiae pheromone response by down-modulating the G-protein coupled recpetor Ste2. Molecular and Cellular Biology 34(14):2660-81.              

*Co-first author

 

Derek C. Prosser (John Hopkins University)

Position: Postdoctoral Fellow, Wendland Lab

 

Area of Study: Molecular mechanisms and regulation of endocytic vesicle formation

 

Website: http://johnshopkins.academia.edu/DerekProsser

 

Contact: dprosser@jhu.edu

 

Co-authored Papers:

 

Prosser, D.C., A.E. Pannunzio, J.L. Brodsky, J. Thorner, B. Wendland, and A.F. O'Donnell. (2015) α-Arrestins participate in cargo selection for both clathrin-independent and clathrin-mediated endocytosis. The Journal of Cell Science 128 (22): 4220-4234.

 

C.G. Alvaro, A.F. O'Donnell*, D.C. Prosser, A.A. Augustine, A. Goldman, J. Brodsky, M.S. Cyert, B. Wendland, and J. Thorner. (2014) Specific α-arrestins negatively regulate Saccharomyces cerevisiae pheromone response by down-modulating the G-protein coupled recpetor Ste2. Molecular and Cellular Biology 34(14):2660-81.              

*Co-first author

Marcel P. Bruchez, PhD (Carnegie Mellon University)

Position: Associate Professor, Director, Molecular Biosensors and Imaging Center

 

Area of Study: Development of tools for single molecule based super resolution microscopy, protein trafficking and sub-cellular physiology

 

Website: http://bruchez-lab.mbic.cmu.edu/research.php

 

Contact: bruchez@cmu.edu

Co-authored Papers:

Hager, N.A., Kraswoski, C.J., Mackie, T.D., Kolb, A.R., Needham, P.G., Augustine, A.A., Dempsey, A., Szent-Gyorgyi, C., Bruchez, M.P., Bain, D.J., Kwiatkowski, A.V., O'Donnell, A.F., Brodsky, J.L. Select a-arrestins control cell-surface abundance of the mammalian Kir2.1 potassium channel in a yeast model. The Journal of Biological Chemistry. 293 (28):11006-11021.

Christopher Szent-Gyorgyi, PhD (Carnegie Mellon University)

Position: Senior Research Scientist

 

Area of Study: Molecular, Structual, and Cellular Biology

 

Website: http://cmu.academia.edu/ChristopherSzentGyorgyi

 

Contact: css@cmu.edu

Co-authored Papers: 

Hager, N.A., Kraswoski, C.J., Mackie, T.D., Kolb, A.R., Needham, P.G., Augustine, A.A., Dempsey, A., Szent-Gyorgyi, C., Bruchez, M.P., Bain, D.J., Kwiatkowski, A.V., O'Donnell, A.F., Brodsky, J.L. Select a-arrestins control cell-surface abundance of the mammalian Kir2.1 potassium channel in a yeast model. The Journal of Biological Chemistry. 293 (28):11006-11021.

Adam V. Kwiatkowski, PhD (University of Pittsburgh)

Position: Assistant Professor

 

Area of Study: Cardiomyocyte adhesion and cytoskeletal organization at the intercalated disc

 

Website: http://www.kwiatkowskilab.com/

 

Contact: adamkwi@pitt.edu

Co-authored Papers:

Hager, N.A., Kraswoski, C.J., Mackie, T.D., Kolb, A.R., Needham, P.G., Augustine, A.A., Dempsey, A., Szent-Gyorgyi, C., Bruchez, M.P., Bain, D.J., Kwiatkowski, A.V., O'Donnell, A.F., Brodsky, J.L. Select a-arrestins control cell-surface abundance of the mammalian Kir2.1 potassium channel in a yeast model. The Journal of Biological Chemistry. 293 (28):11006-11021.

Anne-Ruxandra Carvunis, PhD (University Pittsburgh)

Position: Assistant Professor

 

Area of Study: the molecular mechanisms of change and innovation in evolution of genomes over time

 

Website: http://www.csb.pitt.edu/faculty/carvunis/

 

Contact: anc201@pitt.edu

Jeremy Thorner, PhD (University of California, Berkeley)

Position: Professor of Biochemistry, Biophysics and Structural Biology

 

Area of Study: Transmembrane and intracellular signal transduction mechanisms

 

Website: http://mcb.berkeley.edu/labs/thorner/

 

Contact: jthorner@berkeley.edu

 

Co-authored Papers:

 

Prosser, D.C., A.E. Pannunzio, J.L. Brodsky, J. Thorner, B. Wendland, and A.F. O'Donnell. (2015) α-Arrestins participate in cargo selection for both clathrin-independent and clathrin-mediated endocytosis. The Journal of Cell Science 128 (22): 4220-4234.

 

O'Donnell, A.F., R. R. McCartney, D. G. Chandrashekarappa, B. Zhang, J. Thorner, and M.C. Schmidt. (2014) 2-Deoxyglucose impairs yeast growth by stimulating Snf1-regulated and α-arrestin-mediated trafficking of hexose transporters 1 and 3 in Saccharomyces cerevisiae. Molecular and Cellular Biology, 35(6):939-55.

 

C.G. Alvaro, A.F. O'Donnell*, D.C. Prosser, A.A. Augustine, A. Goldman, J. Brodsky, M.S. Cyert, B. Wendland, and J. Thorner. (2014) Specific α-arrestins negatively regulate Saccharomyces cerevisiae pheromone response by down-modulating the G-protein coupled recpetor Ste2. Molecular and Cellular Biology 34(14):2660-81.              

*Co-first author

 

O'Donnell, A.F., L. Huang, J. Thorner, and M.S. Cyert. (2013) A calcineurin-dependent switch controls the trafficking function of α-arrestin Aly1/Art6. The Journal of Biological Chemistry. 288 (33): 24063-24080

 

Martha S. Cyert (Stanford University)

Position: Professor of Biology

 

Area of Study: Ca2+-dependent signal transduction, focusing on calcineurin

 

Website: http://web.stanford.edu/group/cyert/Home.html

 

Contact: MCYERT@stanford.edu

 

Papers co-authored with:

 

C.G. Alvaro, A.F. O'Donnell*, D.C. Prosser, A.A. Augustine, A. Goldman, J. Brodsky, M.S. Cyert, B. Wendland, and J. Thorner. (2014) Specific α-arrestins negatively regulate Saccharomyces cerevisiae pheromone response by down-modulating the G-protein coupled recpetor Ste2. Molecular and Cellular Biology 34(14):2660-81.              

*Co-first author

 

O'Donnell, A.F., L. Huang, J. Thorner, and M.S. Cyert. (2013) A calcineurin-dependent switch controls the trafficking function of α-arrestin Aly1/Art6. The Journal of Biological Chemistry. 288 (33): 24063-24080

 

 

Minear, S., A.F. O'Donnell*, G. Giaever, C. Nislow, T. Stearns, and M.S. Cyert. (2011) Curcumin inhibits growth of Saccharomyces cerevisiae through iron chelation. Eukaryotic Cell 10 (11): 1574-81. *Co-first author

 

Piña, F.J., A.F. O'Donnell, S. Pagant, H.L. Piao, J.P. Miller, S. Fields, E.A. Miller, and M.S. Cyert. (2011) Hph1 and Hph2 are novel components of the Sec63/Sec62 posttranslational translocation complex that aid in vacuolar proton ATPase biogenesis. Eukaryotic Cell 10 (1): 63-71.

 

O'Donnell, A.F., A. Apffel, R.G. Gardner, and M.S. Cyert. (2010) α-arrestins Aly1 and Aly2 regulate intracellular trafficking in response to nutrient signaling. Molecular Biology of the Cell 21 (20): 3552-3566. 

(Highlighted publication in MBoC)

 

University of Pittsburgh

 

Room A312 Langley Hall, 

5th & Ruskin
Pittsburgh, PA 15260

 

Phone: 412.648.4289

 

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